
Farxiga is owned by AstraZeneca plc, the British-Swedish pharmaceutical company listed on the London and Nasdaq exchanges under ticker AZN. The dapagliflozin tablet won US FDA approval for type 2 diabetes in 2014 and has since added heart failure and chronic kidney disease indications, generating approximately $6.8 billion in global revenue in fiscal 2025 and ranking among AstraZeneca's best-selling products.
Parent Company
Founded
2014
Status
Publicly Traded
Headquarters
| Brand | Parent Company | Ownership Type |
|---|---|---|
| Farxiga | AstraZeneca PLC | Brand division |
AstraZeneca developed dapagliflozin through the 2000s as part of the emerging SGLT2 inhibitor class, which lowers blood sugar by promoting glucose excretion in urine. The FDA approved Farxiga for type 2 diabetes in January 2014, entering a market dominated by metformin and injectable therapies.
The pivotal DECLARE-TIMI 58 trial demonstrated cardiovascular benefits, and in 2020 the FDA expanded Farxiga's label to include heart failure with reduced ejection fraction, the first SGLT2 inhibitor approved for that use. Chronic kidney disease approval followed in 2021.
These indication expansions transformed Farxiga from a diabetes drug into a multi-organ platform product. Sales climbed from under $2 billion at diabetes-only status to approximately $6.8 billion in fiscal 2025, driven by heart failure and CKD uptake.
Patent protection in the United States extends into the mid-2020s with generic challenges expected from 2026 onward, creating a revenue cliff AstraZeneca is managing through combination products and pipeline replacement.
Is AstraZeneca a British or Swedish company?
AstraZeneca is a British-Swedish company. It was formed in 1999 by merging Sweden's Astra AB with the UK's Zeneca Group. Legally it is a UK public limited company headquartered in Cambridge, England, though it retains major operations in Sweden.
Is AstraZeneca publicly traded?
Yes. AstraZeneca PLC trades primarily on the London Stock Exchange under ticker AZN, where it is one of the largest FTSE 100 companies, and it maintains a secondary listing on Nasdaq under the same ticker.
When was AstraZeneca founded?
AstraZeneca was formed in 1999 through the Astra-Zeneca merger. Its roots extend to 1913, when Astra was founded in Sweden, and to Zeneca's 1993 spin-off from Imperial Chemical Industries.
Who leads AstraZeneca?
Pascal Soriot has been chief executive officer since 2012. He is credited with rebuilding the company's pipeline, rejecting Pfizer's 2014 takeover bid, and driving its current position as a top-tier oncology and rare disease company.
What is AstraZeneca's market position?
AstraZeneca is a top-10 global pharmaceutical company with $58.7 billion in 2025 revenue. It is a global leader in oncology and operates major franchises in CVRM, respiratory, and rare disease, with 16 blockbuster medicines and approximately 94,000 employees.
What are AstraZeneca's biggest products?
Tagrisso, Farxiga, Imfinzi, Lynparza, Soliris, Ultomiris, and Symbicort are among its largest products. Oncology alone generated $25.6 billion in 2025, and the company counts 16 medicines with annual sales above $1 billion.
Farxiga has faced no major recalls. Known adverse effects include genital infections, ketoacidosis risk, and dehydration warnings carried on its label, standard for the SGLT2 class. The FDA required updated labeling on ketoacidosis risk after post-market reports.
AstraZeneca has faced litigation over pricing and patent practices common to major pharmaceutical brands, but no drug-specific safety scandal attaches to Farxiga.
These competing brands operate in the same categories and provide similar products or services. Compare key attributes to understand market positioning and competitive landscape.
| Brand | Parent Company | Country | Founded | Market Position | Primary Market | Gender Target |
|---|---|---|---|---|---|---|
| Boehringer Ingelheim | Germany (Boehringer Ingelheim) | 2014 | Market leader | Global | All Genders | |
| Astrazeneca | United Kingdom (parent AstraZeneca) | 2012 | Niche | Global | All Genders | |
| Boehringer Ingelheim | Germany | 1885 | Market leader | Global | All Genders | |
| Eli Lilly | USA | 1876 | Market leader | Global | All Genders | |
| Sanofi | France | 1973 | Market leader | Global | All Genders | |
| Astrazeneca | United Kingdom | 1999 | Market leader | Global | All Genders |
Healthcare PharmaceuticalsOwned by Boehringer Ingelheim
Empagliflozin SGLT2 inhibitor for type 2 diabetes, heart failure, and kidney disease, co-marketed by Boehringer Ingelheim and Eli Lilly since its 2014 launch.
Healthcare PharmaceuticalsOwned by AstraZeneca PLC
Exenatide extended-release weekly injectable for type 2 diabetes, owned by AstraZeneca since the 2012 Amylin Pharmaceuticals acquisition.
Healthcare PharmaceuticalsOwned by Boehringer Ingelheim
German family-owned pharmaceutical brand behind Jardiance and Spiriva, founded in 1885 and still controlled by the Boehringer family.
Healthcare PharmaceuticalsOwned by Eli Lilly and Company
American pharmaceutical brand behind Mounjaro and Zepbound, owned by publicly traded Eli Lilly and Company founded in Indianapolis in 1876.
Healthcare PharmaceuticalsOwned by Sanofi
French pharmaceutical brand behind Lantus and Dupixent, owned by publicly traded Sanofi SA founded in Paris in 1973.
Healthcare PharmaceuticalsOwned by AstraZeneca PLC
British-Swedish pharmaceutical brand behind Tagrisso and Farxiga, owned by publicly traded AstraZeneca PLC formed by merger in 1999.
Market Positioning: Farxiga competes with 6 brands in the same categories, ranging from mass market to luxury positioning.
Geographic Distribution: Competitors are headquartered across multiple regions, indicating global competition in this market segment.
Brand Heritage: Competitor brands range from established heritage brands to newer market entrants, with founding years spanning several decades.
Looking for brands with different ownership structures? These similar brands are not owned by AstraZeneca PLC, giving you alternative choices that support different corporate structures.
Healthcare PharmaceuticalsOwned by Boehringer Ingelheim
Empagliflozin SGLT2 inhibitor for type 2 diabetes, heart failure, and kidney disease, co-marketed by Boehringer Ingelheim and Eli Lilly since its 2014 launch.
Jardiance is privately owned, unlike Farxiga which is under a publicly traded parent company.
Healthcare PharmaceuticalsOwned by Boehringer Ingelheim
German family-owned pharmaceutical brand behind Jardiance and Spiriva, founded in 1885 and still controlled by the Boehringer family.
Boehringer Ingelheim is privately owned, unlike Farxiga which is under a publicly traded parent company.
Healthcare PharmaceuticalsOwned by Eli Lilly and Company
American pharmaceutical brand behind Mounjaro and Zepbound, owned by publicly traded Eli Lilly and Company founded in Indianapolis in 1876.
Eli Lilly operates independently without a large parent corporation.
Healthcare PharmaceuticalsOwned by Sanofi
French pharmaceutical brand behind Lantus and Dupixent, owned by publicly traded Sanofi SA founded in Paris in 1973.
Sanofi operates independently without a large parent corporation.
Healthcare PharmaceuticalsOwned by Novo Nordisk
Danish pharmaceutical company specializing in diabetes care and obesity treatment. Founded in 1923, headquartered in Bagsvaerd, Denmark. World leader in diabetes care and a leader in obesity treatment with Ozempic, Wegovy, and the investigational CagriSema. CEO Lars Fruergaard Jorgensen departed in March 2025; interim leadership under board chairman Helge Lund until a permanent CEO is appointed.
Novo Nordisk operates independently without a large parent corporation.
Healthcare PharmaceuticalsOwned by Amgen Inc.
Master biotechnology brand of Amgen Inc., the world's largest independent biotech, covering its full portfolio of biologic medicines.
Amgen operates independently without a large parent corporation.
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